Package: TransHDM
Title: High-Dimensional Mediation Analysis via Transfer Learning
Version: 1.1.3
Authors@R: 
    c(
    person(given="Huer", family="Gao", email="26111020050@m.fudan.edu.cn", role=c("aut", "cre","cph")),
    person(given="Lulu", family="Pan", email="25111020061@m.fudan.edu.cn", role = c("aut","cph")),
    person(given="Yongfu", family="Yu", role = c("ctb","cph")),
    person(given="Guoyou", family="Qin", role=c("ctb","cph"))
    )
Description: Provides a framework for high-dimensional mediation
        analysis using transfer learning. The main function TransHDM()
        integrates large-scale source data to improve the detection
        power of potential mediators in small-sample target studies. It
        addresses data heterogeneity via transfer regularization and
        debiased estimation while controlling the false discovery rate.
        The package also includes utilities for data generation
        (gen_simData_homo(), gen_simData_hetero()), baseline methods
        such as lasso() and dblasso(), sure independence screening via
        SIS(), and model diagnostics through source_detection(). The
        methodology is described in Pan et al. (2025)
        <doi:10.1093/bib/bbaf460>.
License: GPL (>= 3)
URL: https://github.com/Gaohuer/TransHDM
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
Depends: R (>= 4.0.0)
Imports: glmnet (>= 4.1-10), caret (>= 7.0-1), MASS (>= 7.3-61),
        doParallel (>= 1.0.17), foreach (>= 1.5.2), HDMT (>= 1.0.5),
        ggplot2 (>= 3.4.0)
Suggests: knitr (>= 1.50), rmarkdown (>= 2.30), spelling (>= 2.3.2),
        dplyr (>= 1.0.0), tidyr (>= 1.0.0), ggrepel (>= 0.9.0)
Language: en-US
VignetteBuilder: knitr
LazyData: true
Config/roxygen2/version: 8.0.0
Config/pak/sysreqs: libicu-dev
Repository: https://gaohuer.r-universe.dev
Date/Publication: 2026-08-24 08:11:34 UTC
RemoteUrl: https://github.com/gaohuer/transhdm
RemoteRef: HEAD
RemoteSha: b6fabb41c5e0a1bead03505f7b2520f10240f9de
NeedsCompilation: no
Packaged: 2026-10-23 11:00:34 UTC; root
Author: Huer Gao [aut, cre, cph],
  Lulu Pan [aut, cph],
  Yongfu Yu [ctb, cph],
  Guoyou Qin [ctb, cph]
Maintainer: Huer Gao <26111020050@m.fudan.edu.cn>