# --------------------------------------------
# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
# --------------------------------------------
 
cff-version: 1.2.0
message: 'To cite package "TransHDM" in publications use:'
type: software
license: GPL-3.0-or-later
title: 'TransHDM: High-Dimensional Mediation Analysis via Transfer Learning'
version: 1.0.1
doi: 10.1093/bib/bbaf460
identifiers:
- type: doi
  value: 10.32614/CRAN.package.TransHDM
abstract: Provides a framework for high-dimensional mediation analysis using transfer
  learning. The main function TransHDM() integrates large-scale source data to improve
  the detection power of potential mediators in small-sample target studies. It addresses
  data heterogeneity via transfer regularization and debiased estimation while controlling
  the false discovery rate. The package also includes utilities for data generation
  (gen_simData_homo(), gen_simData_hetero()), baseline methods such as lasso() and
  dblasso(), sure independence screening via SIS(), and model diagnostics through
  source_detection(). The methodology is described in Pan et al. (2025) <https://doi.org/10.1093/bib/bbaf460>.
authors:
- family-names: Gao
  given-names: Huer
  email: gaohuer@proton.me
- family-names: Pan
  given-names: Lulu
  email: 25111020061@m.fudan.edu.cn
preferred-citation:
  type: article
  title: Transfer learning reveals the mediating mechanisms of cross-ethnic lipid
    metabolic pathways in the association between APOE gene and Alzheimer's disease
  authors:
  - family-names: Pan
    given-names: Lulu
    email: 25111020061@m.fudan.edu.cn
  - family-names: Liu
    given-names: Yahang
  - family-names: Huang
    given-names: Chen
  - family-names: Lin
    given-names: Ruilang
  - family-names: Yu
    given-names: Yongfu
  - family-names: Qin
    given-names: Guoyou
  journal: Briefings in Bioinformatics
  year: '2025'
  volume: '26'
  issue: '5'
  doi: 10.1093/bib/bbaf460
  start: bbaf460
repository: https://gaohuer.r-universe.dev
repository-code: https://github.com/Gaohuer/TransHDM
commit: 06b1d7b919217342e9e8137a3a196d7bc03e7211
url: https://github.com/Gaohuer/TransHDM
date-released: '2026-03-24'
contact:
- family-names: Gao
  given-names: Huer
  email: gaohuer@proton.me
references:
- type: manual
  title: 'TransHDM: High-dimensional Mediation Analysis via Transfer Learning'
  authors:
  - family-names: Gao
    given-names: Huer
  - family-names: Pan
    given-names: Lulu
  - family-names: Yu
    given-names: Yongfu
  - family-names: Qin
    given-names: Guoyou
  year: '2026'
  notes: R package version 1.0.0